Creation myths are a fundamental aspect of African cultural heritage, offering insights into the origins of their respective societies and natural worldviews. In Guinea, these myths vary across different ethnic groups and regions, reflecting unique historical and environmental contexts. The research employs a comparative methodological approach, integrating qualitative analysis from interviews with local community leaders and scholars. Data collection covers traditional oral traditions and modern interpretations of creation myths in Guinea’s diverse cultural landscapes. A notable theme emerging from the study is the recurring depiction of water as a central element in creation stories across multiple Guinean cultures, suggesting an influence of Guinea's geographical features on these narratives. This comparative analysis underscores the importance of preserving and understanding cultural myths within contemporary contexts to foster mutual respect and intercultural dialogue among Guinea’s diverse ethnic groups. Promoting educational programmes that integrate traditional creation myths into school curricula could enhance cross-cultural awareness and appreciation. Encouraging collaborative research projects between Guinean scholars and international experts would further enrich the study of these cultural narratives.