E-cigarette usage among urban youth has become a significant public health concern in South African cities following interventions aimed at reducing exposure to tobacco products. A cross-sectional survey was conducted using a convenience sampling method in four major cities. Data were collected through self-administered questionnaires designed by researchers to measure demographics, attitudes towards smoking, and current e-cigarette usage. The findings indicate that despite public health interventions, approximately 25% of urban youth reported using e-cigarettes, with higher prevalence observed among males (30%) compared to females (18%). This study provides valuable insights into the persistence and patterns of e-cigarette use in South African urban youth populations post-intervention. Public health strategies should focus on comprehensive education programmes targeting both adolescents and parents to prevent initiation and reduce usage. Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.