This article explores comparative business dynamics across African regions, focusing on Libya as a case study within the broader field of comparative business studies. This article employs qualitative comparative analysis, integrating insights from existing literature on African economies with specific data collected from Libya. The theoretical framework underscores the importance of addressing specific regional factors to foster sustainable economic growth in Libya and similar African settings. Policy recommendations include streamlining regulatory processes, enhancing access to finance, and promoting a conducive business climate that supports innovation and entrepreneurship.