This article examines Digital Platforms and Monopoly Power: Regulatory Challenges in African Markets: A Subaltern Perspective with a focused emphasis on Ghana within the field of Business. It is structured as a commentary that organises the problem, the strongest verified scholarship, and the main analytical implications in a concise publication-ready format. The paper foregrounds the most relevant institutional, policy, or theoretical dynamics for the African context and closes with a practical conclusion linked to the core argument.