District hospitals in South Africa play a critical role in healthcare delivery but often face challenges in resource utilization and service quality. A mixed-method approach combining quantitative data from hospital records with qualitative interviews to assess system performance. District hospitals in this study exhibited an average yield improvement rate of 15% after implementing process optimization measures. The quasi-experimental design successfully captured the impact of intervention strategies on operational efficiency, providing a robust framework for future improvements. Further research should explore scalability and sustainability of identified interventions across different district hospital settings in South Africa. Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.