Sub-Saharan Africa (SSA), particularly Tanzania, faces significant gender disparities in business participation and outcomes. Qualitative interviews with 50 female and 50 male entrepreneurs across various sectors were conducted to gather insights into their experiences and challenges. Female entrepreneurs reported facing more obstacles in accessing finance and networks compared to males, though they demonstrated higher resilience and innovative approaches to business challenges. Gender disparities persist but are nuanced; strategic interventions targeting financial access and mentorship programmes could enhance gender equality in Tanzanian small businesses. Implement targeted training for female entrepreneurs on securing finance and networking opportunities, alongside fostering a supportive environment that values diverse leadership styles.