Mobile health clinics (MHCs) are increasingly being used in malaria prevention programmes for under-five children in Benin City, Nigeria. A meta-analysis was conducted using data from studies published between and . The average user acceptance rate across the included studies was found to be 68%, with a confidence interval of [64, 72]. MHCs are moderately accepted by parents or guardians but further interventions are needed to enhance usage. Public health campaigns should highlight the benefits and convenience of using MHCs for malaria prevention. user acceptance, mobile health clinics, malaria prevention, under-five children, Benin City Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.