This Data Descriptor focuses on evaluating methods for risk reduction in manufacturing systems within South African industries from to . A panel data model will be employed, incorporating fixed effects to account for plant-specific characteristics. The econometric framework is specified as follows: $y_{it} = eta_0 + eta_1 X_{it} + u_i + v_t + e_{it}$, where $y_{it}$ represents the risk reduction measures in manufacturing system $i$ at time $t$, and $X_{it}$ includes variables such as investment levels, regulatory adherence, and workforce training. The uncertainty around $eta_1$ is estimated with robust standard errors to reflect potential model misspecification. Panel data analysis reveals a significant positive correlation between increased investments in risk management measures (e.g., insurance, emergency preparedness) and reduced operational risks across the manufacturing sector in South Africa. This study underscores the importance of consistent monitoring and investment in preventive strategies for enhancing safety and efficiency in South African manufacturing environments. Manufacturing companies should prioritise ongoing risk assessment and proactive investments to align with best practices, thereby improving their resilience against potential disruptions. South Africa, Manufacturing Systems, Panel Data Estimation, Risk Reduction, Econometrics