Ghana faces challenges in maintaining soil health due to intensive farming practices, leading to decreased fertility and productivity. Agricultural field trials were conducted across three regions in Ghana, employing mixed methods including surveys and soil analysis to assess changes in soil organic matter content (SOC) over two growing seasons. Inter-cropping with leguminous plants significantly increased SOC by an average of 15% compared to monoculture practices, although the effect was more pronounced in regions with higher rainfall. Agroecological approaches have shown promise in improving soil health and fertility, particularly when integrated with local agricultural knowledge and resources. Farmers should be provided with training on agroecological practices and access to locally produced compost as a cost-effective means of enhancing soil quality. Soil Fertility, Agroecology, Ghana, Inter-cropping, Composting The empirical specification follows $Y=\beta_0+\beta^\top X+\varepsilon$, and inference is reported with uncertainty-aware statistical criteria.