Mobile health services have emerged as a critical tool for addressing healthcare disparities in resource-limited settings such as Nigeria. The research employs mixed-methods including quantitative surveys and qualitative interviews to assess participants' adherence to treatment regimens and health status over six years. A notable finding is that 75% of participants maintained their prescribed medication regimen, significantly improving their long-term HIV outcomes compared to traditional healthcare approaches. Mobile health services appear to offer a viable alternative for delivering consistent care to HIV-positive Nigerian women in urban areas. Healthcare providers should consider integrating mobile health solutions into broader treatment programmes to enhance patient engagement and adherence.