Non-communicable diseases (NCDs) pose significant health challenges in urban centers of Uganda, where youth advocacy is crucial for improving awareness and literacy. A mixed-methods approach combining quantitative surveys with qualitative interviews to analyse health literacy levels and thematic content of advocacy materials. Analysing survey responses from to , a significant increase in awareness about hypertension (from 45% to 68%) was observed, alongside notable growth in diabetes knowledge (from 32% to 50%). Youth advocacy has effectively raised NCD literacy levels, particularly for hypertension and diabetes, highlighting the need for sustained educational efforts. Continue fostering youth-led initiatives with regular updates on emerging health issues, ensuring culturally relevant education materials are available. Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.