Intellectual Property (IP) law in Africa is a growing field of study, with significant implications for technology transfer within African universities. Senegal is one such country where these dynamics are emerging. The study employs a comparative legal analysis, drawing on existing laws, scholarly literature, and case studies from Senegal as well as other African nations. This theoretical framework provides insights into how IP law can be better adapted to support technology transfer in Senegalese universities, focusing on issues of equitable compensation and transparent governance. Recommendations include advocating for legislative amendments that enhance the legal protections for inventors within university frameworks and promoting more transparent mechanisms for resolving disputes over intellectual property rights.