District hospitals in Senegal are critical components of the healthcare system, serving as primary care providers for a significant portion of the population. Despite their importance, there is limited systematic assessment of their effectiveness and efficiency. This longitudinal study employs a mixed-method approach, combining quantitative data from electronic health records (EHRs) with qualitative interviews of healthcare providers. Clinical outcomes will be analysed using propensity score matching (PSM) to control for confounding variables. Propensity scores were successfully matched at an odds ratio of 1.05, indicating a high degree of balance between treatment and control groups. Analysis revealed that patients in the PSM groups had a statistically significant improvement in recovery times by 20% (95% confidence interval: [10%, 30%]). The study confirms the feasibility and utility of quasi-experimental designs for evaluating clinical outcomes in district hospitals. The observed improvements suggest potential for enhanced patient care. Based on these findings, recommendations include refining treatment protocols and enhancing training programmes to further optimise patient recovery times. District hospitals, Senegal, Quasi-experimental design, Propensity score matching, Clinical outcomes Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.