In Ghanaian rural communities in Guinea, the use of insect repellent bed nets (IRBNs) is essential for controlling malaria transmission. A mixed-method approach combining quantitative data from surveys and qualitative insights from focus group discussions was employed. Insect repellent bed nets were predominantly adopted by women (75%) in households with children under five years, indicating gendered usage patterns. The study underscores the importance of targeted distribution strategies to ensure equitable access and long-term use of IRBNs. Policy recommendations include prioritising community engagement for sustained adoption and implementation of innovative distribution models.