Health systems in Nigeria have faced numerous challenges during epidemic responses, necessitating a deeper understanding of resilience strategies. Qualitative research methods were employed, including semi-structured interviews and document analysis among healthcare workers and government officials. Healthcare facilities reported significant delays in receiving essential medical supplies, affecting patient flow and care delivery during the Ebola outbreak in . The study underscores the need for improved supply chain management to enhance health system resilience in future epidemics. Implementing robust supply chain protocols and strengthening inter-agency coordination are recommended.