Digital transformation in retail sectors across North Africa is gaining momentum, particularly in Ghana where traditional brick-and-mortar stores are increasingly integrating digital technologies to enhance customer experiences and operational efficiencies. A systematic review approach is employed to synthesize existing literature and conduct an in-depth analysis of relevant theoretical frameworks related to digital transformation and business operations. This theoretical framework provides foundational insights into the complex interplay between digital technologies and business operations within North African retail sectors. It highlights areas for further empirical research and practical application of these findings. Retail businesses in Ghana should prioritise investments in digital infrastructure, training employees on new technologies, and engaging with customers through innovative digital channels to stay competitive and customer-centric.