Eco-friendly waste management systems have been implemented in Kampala’s informal settlements to address environmental challenges and improve public health. A mixed-methods approach including surveys, interviews, and observational studies was employed to gather data from residents and waste management personnel in selected informal settlements. Household garbage reduction rates averaged 30% over the two-year period, with significant improvements noted in composting of organic waste, reducing methane emissions by 25% compared to traditional disposal methods. The eco-friendly waste management systems demonstrated substantial environmental benefits and community engagement, providing a model for sustainable waste handling in similar settings. Continue pilot projects with wider implementation, enhance public education campaigns, and integrate technological solutions for improved data collection and dissemination of results.