Mentoring programmes have been identified as effective tools for fostering entrepreneurship among young individuals in various sectors and regions. However, their impact on female youth entrepreneurs specifically within Nairobi’s informal sector remains underexplored. The study employs a qualitative analysis approach, drawing on existing literature and expert insights to develop a comprehensive theoretical model. This framework underscores the need for culturally sensitive mentoring initiatives to address unique challenges faced by female entrepreneurs in Nairobi's diverse cultural landscape. Policy makers should consider incorporating these findings into their support programmes, emphasising tailored mentorship and community engagement as essential components.