African Livestock Production Science (Health focus) | 25 November 2011
Urban Healthcare Antibiotic Resistance Evaluation Over Two Years in Johannesburg, South Africa: Patient Outcomes
M, a, n, d, i, s, a, K, h, u, m, a, l, o, ,, S, i, p, h, o, M, o, t, s, h, e, g, a, ,, N, o, n, t, a, b, a, N, k, o, t, s, h, w, a, ,, Z, o, l, a, C, e, l, e
Abstract
This study evaluates antibiotic resistance levels in urban healthcare facilities within Johannesburg, South Africa. A cross-sectional analysis was conducted using data from all patients treated at participating healthcare facilities. Antibiotic susceptibility testing followed the Kirby-Bauer method. Antibiotic resistance rates varied significantly, with a proportion exceeding 50% for certain bacterial strains in urban settings compared to rural areas. Urban healthcare environments contribute disproportionately to antibiotic-resistant bacteria, necessitating targeted interventions. Enhanced surveillance and infection control measures are recommended to mitigate the spread of antibiotic resistance. Treatment effect was estimated with $\text{logit}(p<em>i)=\beta</em>0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.