Implementing and Accepting HIV Pre-exposure Prophylaxis among Key Populations in Kenya: A Mixed Methods Study

HIV remains a significant public health challenge in Kenya, particularly among key populations such as sex workers and men who have sex with men (MSM). A mixed methods study combining quantitative surveys, qualitative interviews, and observational data collection. The survey used a validated PrEP adherence scale to measure uptake and effectiveness. Among the key populations surveyed, 45% reported using PrEP consistently over six months, with perceived side effects being the most common reason for non-adherence. PrEP is acceptable but not fully adopted by key populations in Kenya; addressing stigma and improving access are crucial to its wider implementation. Integrate community-based health education programmes that address both PrEP benefits and side effect concerns. Enhance PrEP availability through mobile clinics targeting high-risk groups.