Recent studies have highlighted the need for robust monitoring networks in Ghana to assess environmental health outcomes effectively. The methodology employed a systematic search of literature databases including PubMed, Google Scholar, and Scopus. Studies were selected based on specific criteria such as use of quasi-experimental designs for clinical outcomes measurement in Ghanaian settings. A total of 15 studies met the inclusion criteria, with a majority focusing on water quality monitoring networks across different regions of Ghana. The review found that while some regional monitoring networks demonstrated significant improvements in water quality, there was variability in their effectiveness and consistency over time. Enhancing data collection methods and improving network coordination are recommended to improve the reliability and impact of environmental health assessments. The empirical specification follows $Y=\beta_0+\beta^\top X+\varepsilon$, and inference is reported with uncertainty-aware statistical criteria.