The replication study aims to evaluate the manufacturing systems in Kenyan clinics, with a focus on their effectiveness and reliability in producing clinical supplies. A robust design was employed for the replication study, including random assignment of clinics to control and intervention groups. Data collection focused on clinical outcomes measured using standardised protocols. In the analysed sample of 120 Kenyan clinics, a significant improvement in drug efficacy (p < 0.05) was observed when manufacturing systems were optimised according to best practices. The study underscores the importance of consistent quality control measures and standardised procedures for optimal performance of clinical manufacturing systems. Healthcare providers are advised to adopt recommended standards for manufacturing processes, which can enhance patient care and reduce adverse events associated with substandard supplies. The empirical specification follows $Y=\beta_0+\beta^\top X+\varepsilon$, and inference is reported with uncertainty-aware statistical criteria.