In Uganda, livestock plays a crucial role in rural economies, particularly for women who often manage these assets. However, livestock are vulnerable to disasters and diseases, leading to significant economic losses. A mixed-methods approach including pre- and post-intervention surveys, focus group discussions, and interviews was employed. Quantitative data were analysed using descriptive statistics and inferential statistical models. Women who received gender-specific insurance coverage reported a significant reduction in economic stress (p < 0.05) compared to those without insurance. Gender-specific livestock insurance has demonstrated potential for improving the economic resilience of rural women in Uganda, with specific effects observed within six months post-intervention. Policy makers should consider implementing gender-sensitive insurance programmes as a means to support and empower rural women economically. The empirical specification follows $Y=\beta_0+\beta^\top X+\varepsilon$, and inference is reported with uncertainty-aware statistical criteria.