Waste management in Kampala's informal settlements faces significant challenges due to inadequate infrastructure and resources. The study employed qualitative case studies of three distinct social entrepreneurship initiatives operating within the same geographical area. A preliminary analysis indicates a $1:2.5$ return on investment in terms of increased employment opportunities and reduced waste disposal costs among participants. Social entrepreneurship models have demonstrated potential for enhancing community resilience and economic sustainability in Kampala's informal settlements. Further research should focus on scaling up successful initiatives while addressing scalability challenges.