Tuberculosis (TB) remains a significant public health concern in urban areas of Ghana, including Accra. Community-led screening programmes are increasingly being implemented to improve early detection and treatment. A mixed-methods approach was employed, including baseline surveys, follow-up interviews, and analysis of sputum samples collected during the screening process. Data were analysed using descriptive statistics and logistic regression models. The annual sputum culture success rate improved from 45% to 60%, indicating a significant increase in detection rates. Treatment adherence among those diagnosed with TB was also observed to be higher than expected at around 80%. These findings suggest improvements in both detection and treatment outcomes. The community-led screening programme demonstrated positive effects on case detection rates, particularly in terms of sputum culture success rate and treatment adherence. Further research is recommended to explore long-term impacts and scalability. Expanding the programme to other urban areas and incorporating continuous training for healthcare workers can enhance its effectiveness and reach more residents. Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.