Ghana's Eastern Region has seen a significant maternal mortality rate (MMR), necessitating innovative interventions to improve health outcomes. The study employed a mixed-methods approach involving baseline surveys and follow-up assessments among CHW-managed communities. Data were analysed using descriptive statistics to assess changes in MMR over time. CHWs reported reductions of 25% in MMR, with a notable decrease in severe obstetric hemorrhage cases (34%), supported by robust standard errors and 95% confidence intervals indicating the reliability of these findings. This study provides preliminary evidence that CHW interventions can effectively reduce maternal mortality rates in Ghana's Eastern Region, highlighting their critical role in rural health care delivery. Further research should be conducted to validate these results and explore scalability and cost-effectiveness of such programmes. maternal mortality reduction, community health workers, mixed-methods evaluation Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.