The East African region is characterized by a diverse array of entrepreneurship ecosystems and innovation hubs that play significant roles in fostering economic development. A comprehensive literature review will be conducted to identify existing models and frameworks for entrepreneurship ecosystems and innovation hubs. This will inform the development of a theoretical model. This theoretical framework provides a solid foundation for understanding and potentially improving entrepreneurship ecosystems and innovation hubs in Morocco and other East African countries. Future research should focus on empirical validation of the proposed model through case studies and longitudinal analyses.