This article examines Populism in Africa: Definitions, Cases, and Analytical Frameworks: Applied to the Greater Horn of Africa with a focused emphasis on Guinea-Bissau within the field of Political Science. It is structured as a theoretical framework article that organises the problem, the strongest verified scholarship, and the main analytical implications in a concise publication-ready format. The paper foregrounds the most relevant institutional, policy, or theoretical dynamics for the African context and closes with a practical conclusion linked to the core argument.