E-health education workshops have been introduced in primary schools to enhance students' digital literacy skills in Ghana. A comprehensive search strategy was employed to identify relevant studies. Studies were included if they met specific criteria related to methodology and outcomes measurement. The analysis revealed a statistically significant improvement in students' e-learning skills (p < 0.05), with an effect size of d = 0.82, indicating substantial learning gains. E-health education workshops appear effective in enhancing digital literacy among primary school students in the context of Equatorial Guinea. Further longitudinal studies should be conducted to explore long-term effects and potential improvements in teaching methods.