Youth mental health issues are prevalent in Nigerian universities, necessitating effective awareness programmes. A comprehensive search strategy was employed to identify relevant studies. Data were extracted using standardised forms, and findings were synthesized following PRISMA guidelines. Statistical analysis included meta-regression models with robust standard errors. Findings indicated a moderate improvement in student mental health knowledge scores post-programme (mean increase of 15% with 95% CI: 8%, 23%). This study highlights the need for sustained and evidence-based mental health awareness initiatives in Nigerian universities. Universities should prioritise regular, validated mental health education programmes to enhance student well-being. Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.